Timothy Donahue, Ph.D.
Teaching Assistant Professor
820 W Franklin, rm 208
My research and area of interest is behavioral pharmacology, specifically the discriminative stimulus properties of antipsychotic medications. I have been investigating a medication called amisulpride, an atypical antipsychotic, produced by the French pharmaceutical company Sanofi-Aventis and used in the treatment of schizophrenia and depression. It is not approved for use in the USA but is widely used throughout Europe and Australia. Amisulpride has a distinctive receptor binding profile. My research has demonstrated that the amisulpride stimulus is readily acquired in C57BL/6 mice; and that the drug possesses a unique and robust discriminative stimulus that is dose-dependent, time-dependent and stereoselective and is not shared with other antipsychotic or antidepressant drugs.
Donahue, T. J., Hillhouse, T. M., Webster, K. A., Young, R., De Oliveira, E. O., & Porter, J. H. (2017). Discriminative stimulus properties of the atypical antipsychotic amisulpride: comparison to its isomers and to other benzamide derivatives, antipsychotic, antidepressant, and antianxiety drugs in C57BL/6 mice. Psychopharmacology, 234, 3507-3520.
Donahue, T. J., Hillhouse, T. M., Webster, K. A., Young, R., De Oliveira, E. O., & Porter, J. H. (2014). (S)-amisulpride as a discriminative stimulus in C57BL/6 mice and its comparison to the stimulus effects of typical and atypical antipsychotics. European Journal of Pharmacology, 734, 15-22.
- Biological Psychology, graduate level
- Psychology and Law, undergraduate level
- Freud: Myths and Legacy, undergraduate level
- Introduction to Psychology, undergraduate level
- Physiological Psychology, undergraduate level
- Perception, undergraduate level
- History of Psychology, undergraduate level
- Faculty Council Research Award by the College of Humanities and Sciences, Virginia Commonwealth University, 2015
- Graduate Student Research Award, Society for the Stimulus Properties of Drugs, 2011